books library land

Sample Size Calculations In Clinical Research Third Edition PDF

Book Description:

Sample Size Calculations In Clinical Research Third Edition PDF

Praise for the Second Edition:

“… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study.”Biometrics

This impressive book contains formulae for computing sample size in a wide range of settings. One-sample studies and two-sample comparisons for quantitative, binary, and time-to-event outcomes are covered comprehensively, with separate sample size formulae for testing equality, non-inferiority, and equivalence. Many less familiar topics are also covered …” – Journal of the Royal Statistical Society

Sample Size Calculations in Clinical Research, Third Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. A comprehensive and unified presentation of statistical concepts and practical applications, this book includes a well-balanced summary of current and emerging clinical issues, regulatory requirements, and recently developed statistical methodologies for sample size calculation.

Features:

  • Compares the relative merits and disadvantages of statistical methods for sample size calculations
  • Explains how the formulae and procedures for sample size calculations can be used in a variety of clinical research and development stages
  • Presents real-world examples from several therapeutic areas, including cardiovascular medicine, the central nervous system, anti-infective medicine, oncology, and women’s health
  • Provides sample size calculations for dose response studies, microarray studies, and Bayesian approaches
  • This new edition is updated throughout, includes many new sections, and five new chapters on emerging topics: two stage seamless adaptive designs, cluster randomized trial design, zero-inflated Poisson distribution, clinical trials with extremely low incidence rates, and clinical trial simulation.

    Book Details:

    Sample Size Calculations In Clinical Research Third Edition PDF

    Author Shein-Chung Chow
    Isbn 1138740985
    File size 81.3 MB
    Year 2017
    Pages 510
    Language English
    File format PDF
    Category Mathematics

    Download the Book
    Buy Book From Amazon

    Products you may like

    Related Products

    Add comment

    Categories

    You May Like These

    Your Header Sidebar area is currently empty. Hurry up and add some widgets.